Southeast Asian Journal of Case Report and Review
Official Publication of Association of Biomedical Scientists
Official Publication of Association of Biomedical Scientists
Online ISSN: 2319-1090
Southeast Asian Journal of Case Report and Review is a Peer-reviewed, International medical journal Published by the Association of Health Professionals. It will publish 04 issues per year will publish a research paper prepared by Health Professional. Journal will Give Preference to Case Report and Review Article Aim and Scope The aim and commitment of the journal is to publish a research-oriented manuscript on significant issues in all the subjects and areas of Medical Science including Genome mutation and Pathogenicity in microbes. Journal more...Case Report
Author Details :
Volume : 11, Issue : 1, Year : 2024
Article Page : 6-9
https://doi.org/10.18231/j.sajcrr.2024.002
Abstract
Extrapulmonary tuberculosis is a very common cause of generalised lymphadenopathy especially in tuberculosis endemic regions like India. A 33-year-old lady who had been diagnosed with rheumatoid arthritis 5 years back and had received treatment with biologicals including adalimumab presented with a 3 week history of persistent fever associated with significant weight loss and abdominal fullness. Investigations pointed towards a picture of tubercular aetiology although, a definite microbiological diagnosis was not possible at this stage. Patient also had an underlying subacute thyroiditis with diffusely increased uptake in Tc99 scan. Considering the background risk factor of use of biologicals and typical clinical presentation resembling tuberculosis, a decision to start antitubercular therapy was taken. The fever resolved but it recurred after 2 weeks and then after an extensive workup, the diagnosis of coexistent IgG4-related disease along with microbiological diagnosis of tuberculosis was established. This case highlights the importance of an active search for coexistent pathologies in cases of lymphadenopathy with insufficient response to standard therapy.
Keywords: IgG4-related disease, Lymphadenopathy, Subacute thyroiditis, Tuberculosis, Castleman’s disease
How to cite : Chandra S K, Dastidar A G, Singhal P, Sengupta S, Bandyopadhyay S, Coexistence of IgG4-related disease and tubercular lymphadenopathy in a rheumatoid arthritis patient. South Asian J Case Rep Rev 2024;11(1):6-9
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