Southeast Asian Journal of Case Report and Review

Online ISSN: 2319-1090

Southeast Asian Journal of Case Report and Review is a Peer-reviewed, International medical journal Published by the Association of Health Professionals. It will publish 04 issues per year will publish a research paper prepared by Health Professional. Journal will Give Preference to Case Report and Review Article   Aim and Scope The aim and commitment of the journal is to publish a research-oriented manuscript on significant issues in all the subjects and areas of Medical Science including Genome mutation and Pathogenicity in microbes. Journal more...

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Review Article


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1- 4


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Bibekananda Bhoi , Himanshu Bhardwaj*, Maneesh Kumar


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A review of the SARS-CoV-2 viral genome mutation and its effects


Review Article

Author Details : Bibekananda Bhoi , Himanshu Bhardwaj*, Maneesh Kumar

Volume : 10, Issue : 1, Year : 2023

Article Page : 1-4

https://doi.org/10.18231/j.sajcrr.2023.001



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Abstract

The pandemic-starting SARS-CoV-2 novel coronavirus was found in Wuhan, China. WHO declared this pandemic, which began in late 2019, in March 2020. Experts say this was the first SARS-CoV-2 outbreak. It was the first of many. This virus constantly mutates in response to its replication environment, causing waves, the deadliest of which was the delta variant-caused second wave, which killed millions worldwide. This review examines viral genome alterations and their global effects. We used references from previous research articles on this or similar issues to make our review more data-driven. We found that the virus' mutation has caused major health problems in humans, including deaths. The viruses changed genome, proteins, local food, sanitation, immunity, and milieu may be involved. We also found that while some of the impacted variations are milder and less contagious, some have had record-breaking peaks and significant death rates in a short time. This analysis examines COVID-19's impact on diabetes, cardiovascular disease, asthma, aging, and community hygiene. SARS-CoV-2 increases stress and blood glucose in diabetics. Clinical investigations have linked COVID-19 to cardiovascular disease, although the mechanism is uncertain. Asthmatics are more vulnerable to respiratory infections. Its effects change as one age. Cleanliness campaigns are needed to put an end to the epidemic.
Keywords : SARS­CoV­2, COVID­19, Mutation, Diabetes, Cardiovascular Diseases, Asthma


How to cite : Bhoi B, Bhardwaj H, Kumar M, A review of the SARS-CoV-2 viral genome mutation and its effects. South Asian J Case Rep Rev 2023;10(1):1-4

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